mRNA at Synapses, Synaptic Plasticity, and Memory Consolidation
نویسنده
چکیده
Miller et al. (this issue of Neuron) report that deletion of the 3'UTR of alpha-CaMKII mRNA prevents dendritic delivery of the mRNA in transgenic mice and thus local synthesis of alpha-CaMKII protein in dendrites. 3'UTR mutant mice exhibit decreases in alpha-CaMKII protein in postsynaptic densities, and deficits in late phase LTP and in memory consolidation.
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ورودعنوان ژورنال:
- Neuron
دوره 36 شماره
صفحات -
تاریخ انتشار 2002